Mercedes S Class w221 (2005 – 2013)  – fuse box diagram

Mercedes S Class w221 (2005 – 2013)  – fuse box diagram

Year of production: 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013

Fuse box in the engine compartment

Mercedes-Benz S-Class - w221 - fuse box diagram - engine compartment
Mercedes-Benz S-Class – w221 – fuse box diagram – engine compartment
Number Fused fucntion Ampere ratting [A]
20 Valid for engine 629, 642, 651:
CDI control unit
Valid for engines 156, 157, 272, 273, 275, 276, 278:
ME-SFI [ME] control unit
10
21 Valid for engines 156, 157, 272, 273, 275, 276, 278:
Terminal 87 M1 i connector sleeve
Valid for model 221 with engine 629 and engine 642:
CDI control unit
Fuel pump relay
Valid for model 221 with engine 651:
Quantity control valve
20
22 Valid for engines 156, 157, 272, 273, 276, 278:
Terminal 87 connector sleeve
15
23 up 2008:
Terminal 87 connector sleeve
Valid for engine 275 (model 216):
Terminal 87 M1 i connector sleeve
Valid for engine 273 (model 216):
Terminal 87 M2e connector sleeve
Valid for engine 272, 273 (model 221):
Terminal 87M2i connector sleeve
Valid for engine 642:
Terminal 87 connector sleeve
from 2009:
Valid for engine 156, 157, 272, 273, 275, 276, 278:
Terminal 87 connector sleeve
Valid for model 221 with engine 629 and engine 642:
Terminal 87 connector sleeve
Valid for engine 156, 157, 272, 273, 276, 278:
Terminal 87M2e connector sleeve
Valid for engine 275:
Terminal 87 M2i connector sleeve
Valid for model 221 with engine 629 and engine 642:
Terminal 87 connector sleeve
Valid for model 221 with engine 651:
Rear SAM control unit with fuse and relay module
20
24 Valid for engines 157, 272, 273, 276, 278:
Terminal 87M1e connector sleeve
Valid for engine 642:
CDI control unit
25
25 Instrument cluster 7,5
26 Left front lamp unit 10
27 Right front lamp unit 10
28 Valid for engine 275:
EGS control unit
Valid without engine 275:
Fully integrated transmission control (VGS) control unit
7,5
29 Rear SAM control unit with fuse and relay module 5
30 Valid for engine 629, 642, 651:
CDI control unit
Valid for engines 156, 157, 272, 273, 275, 276, 278:
ME-SFI [ME] control unit
Fuel pump control unit
7,5
31 S 400 Hybrid: Electric refrigerant compressor 5
32 Valid for model with ECO start/stop function: 
Transmission oil auxiliary pump control unit
S 400 Hybrid:
Transmission oil auxiliary pump control unit 
15
33 Valid as of 1.9.10 without model S 400 Hybrid:
ESP control unit
S 400 Hybrid:
Battery management system control unit
DC/DC converter control unit
Power electronics control unit 
5
34 S 400 Hybrid: Regenerative braking system control unit 5
35 Electric parking brake controller unit  5
36 Data link connector (Pin 16) 10
37 For EIS control unit  7,5
38 Central gateway control unit 7,5
39 Instrument cluster  7,5
40 Upper control panel control unit 7,5
41 Slave wiper motor  30
42 Master wiper motor  30
43 Front cigar lighter with ashtray illumination 15
44
45 S 400 Hybrid: Power electronics circulation pump 1 5
46 W221 with Active Body Control (ABC), model 216: ABC control unit
W221 without Active Body Contro (ABC): AIRmatic with ADS control unit
15
47 Front SAM control unit with fuse and relay module
Steering column up/down motor
15
48 up 2008: Front SAM control unit with fuse and relay module
from 2009: Steering column in/out motor
15
49 Steering column module  10
50 AAC [KLA] control unit 15
51 up 2008: COMAND display  7,5
from 2009:
COMAND display
SPLITVIEW display
5
52 A W221:
Left fanfare horn
Right fanfare horn 
15
52 B W221, C216:
Left fanfare horn
Right fanfare horn 
15
53
54 AC air recirculation unit 40
55 Valid for gasoline engine: Electric air pump 60
56 W221 without Active Body Contro (ABC): AIRmatic compressor unit 40
57 up 2008:Wiper park position heater 40
from 2009: Wiper park position heater 30
60 from 2009:Electrohydraulic power steering 5
61 C216; W221 – from 2009: Restraint systems control unit 7,5
W221; up 2008:Restraint systems control unit 10
62 Night View Assist control unit 5
63 Valid for model 221 with engine 629 and engine 642 as of 1.9.08: Fuel filter condensation sensor with heating element 15
64 W221 as of 1.9.06:
Driver NECK-PRO head restraint solenoid
Front passenger NECK-PRO head restraint solenoid
7,5
W221 as of ’09:
Driver NECK-PRO head restraint solenoid
Front passenger NECK-PRO head restraint solenoid
10
65 Valid as of 1.6.09: 12 Volt connector in glove box 15
66 DTR controller unit (Distronic or Distronic Plus) 7,5
Relay
A Air pump relay
B Air suspension compressor relay
C Terminal 87 relay, engine
D Terminal 15 relay
E Terminal 87 relay, chassis
F Fanfare horn relay
G Terminal 15R relay
H Circuit 50 relay, starter
J Circuit 15 relay, starter
K Wiper park heater relay

Left instrument panel fuse box

Mercedes-Benz S- Class w221 - fuse box diagram - left instrument panel
Mercedes-Benz S- Class w221 – fuse box diagram – left instrument panel
Number Fused function Ampere ratting [A]
92 Left front seat control unit 40
93 Restraint systems control unit
USA version: Weight Sensing System (WSS) control unit
7,5
94 from 2009: Multifunction camera 5
95
96 Tire pressure monitor [RDK] control unit 5
97 W221: Audio/video controller control unit (rear entertainment system) 7,5
98 Rear entertainment system: DVD player (from 2009) 7,5
99 from 2009:
COMAND display
SPLITVIEW display
7,5
100 from 2009: Media interface control unit 5
101 Rear entertainment system:
Left rear display
Right rear display
10
102 Right front seat control unit 40
103 ESP control unit 7,5
104 Audio tuner control unit 40
105
106 Japanese version: Electronic toll collection (ETC) control unit
Valid for South Korea as of 1.9.10: TV/tuner connector
Valid for navigation; from 2009: Navigation processor
1
107 SDAR control unit (SIRIUS satellite radio) (W221 from 2009)
Digital radio: Digital Audio Broadcasting control unit
HD radio: High definition tuner control unit
5
108 W221: Rear air conditioning control unit 5
109 W221: Rear blower intermediate connector 15
110 W221:
Left rear multicontour backrest control unit
Right rear multicontour backrest control unit
7,5
111 Rear multicontour seat or rear entertainment system (model 221): RCP [HBF] control unit 5
112 W221; up 2008:
Left front door control unit
Right front door control unit
S 400 Hybrid: Front SAM control unit with fuse and relay module
5
113 S 400 Hybrid: DC/DC converter control unit 5

Right instrument panel fuse box

Mercedes-Benz S- Class w221 - fuse box diagram - right instrument panel
Mercedes-Benz S- Class w221 – fuse box diagram – right instrument panel
Number Fused Function Ampere ratting [A]
70 C216: Right door control unit
W221: Right front door control unit
40
71 Keyless Go control unit 15
72 S 400 Hybrid: Pyrotechnical separator 7,5
73 Japanese version: COMAND controller unit
TELE AID emergency call system (from 2009): Emergency call system control unit
5
74 TLC [HDS] control unit (Remote trunk closing) 30
75 S 400 Hybrid:
Battery management system control unit
Power electronics control unit
10
76 S 400 Hybrid: Vacuum pump relay (+) 15
Valid for model 221 with engine 642.8: AdBlue® relay supply
77 Advanced sound system: Sound amplifier (from 2009) 50
78 S 65 AMG with engine 275:
Additional fan relay (from 2009)
Valid for model 221 with engine 642.8:
AdBlue® relay supply (from 2009)
25
S 400 Hybrid, CL 63 AMG with engine 157, 278:
Charge air cooler circulation pump (from 2009)
15
79 Alarm signal horn with additional battery 7,5
80 C216: Left door control unit
W221: Left front door control unit
40
81 C216: Rear control unit 30
W221: Left rear door control unit 40
82 C216: Rear control unit 30
W221: Left rear door control unit 40
83 Intelligent servo module for DIRECT SELECT 40
84 Advanced sound system: Digital sound processor (from 2009) 20
85 Valid for AMG: Illuminated door sill moldings (from 2009) 10
86
87
88
89
90 Stationary heater:
STH heater unit (model 216)
STH or HB heater unit (model 221)
20
91 Stationary heater:
STH radio remote control receiver
S 400 Hybrid:
Front SAM control unit with fuse and relay module
5

Fuse and relay box in rear

Mercedes-Benz S- Class w221 - fuse box diagram - rear compartment
Mercedes-Benz S- Class w221 – fuse box diagram – rear compartment
Number Fused Function Ampere ratting [A]
115 Heated rear window 50
116 Valid for engine 157, 275, 278: Charge air cooler circulation pump
Valid for engine 156: Engine coolant circulation pump
S 400 Hybrid: Power electronics circulation pump 2
10
117 Rear cigar lighter 15
118 Valid for engine 272, 273, 642: Fuel pump (up 2008)
Valid for model 221 with engine 629, 642: Fuel pump (from 2009)
30
S 400 Hybrid: Power electronics circulation pump 1
Valid for model 642.8 and engine 651 as of 1.6.11: Refrigerant compressor with magnetic
15
119 Front central operating unit 7,5
120
121 Audio tuner control unit 10
122 COMAND controller unit 7,5
123 W221: Right front reversible emergency tensioning retractor 40
124 W221: Left front reversible emergency tensioning retractor 40
125 up 31.5.09: Voice control system (VCS) control unit 5
126 Overhead control panel control unit 25
127 Lumbar pump (from 2009)
Multicontour seat pneumatic pump (Left/right front multicontour seats)
Pneumatic pump for dynamic seat control (Left and right dynamic multicontour seat)
30
128 Valid for engine 275 (up 2008): Fuel pump control unit
Valid for engine 156, 157, 272, 273, 275, 276, 278, 642 (from 2009):Fuel pump control unit
25
129 up 2008: Overhead control panel control unit (Power glass tilting/sliding roof)
from 2009: UPCI (Universal Portable Cell Phone Interface) control unit
25
130 Electric parking brake controller unit 30
131 Rear window antenna amplifier module 7,5
133 Trailer recognition control unit
Reversing camera (as of 1.9.10)
15
134 Luggage compartment socket 15
135 Park Assist; up 2008:
Radar sensors control unit (SGR)
Front short range radar sensor unit
Rear short range radar sensor unit
DISTRONIC PLUS up to 31.8.10 or Blind Spot Assist or Adaptive cruise control Plus Light: Radar sensors control unit (SGR) (from 2009)
PARKTRONIC or Exclusive parking assist: PTS control unit
7,5
136 Valid for model 221 with engine 642.8: AdBlue® control unit 7,5
137 Reversing camera (as of 1.9.10) 7,5
138 Navigation processor (from 2009) (up to 31.8.10)
Emergency call system control unit (from 2009)
Japanese version: TV/tuner connector (from 2009)
5
139 Rear backrest refrigerator box 15
140 Rear cigar lighter with ashtray illumination connector
115 V socket (from 2009)
15
141 Reversing camera control unit 5
142 Parktronic system (PTS) control unit
Distronic Plus: Radar sensors control unit (SGR)
Valid as of 1.9.10 for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist:
Video and radar sensor system control unit
7,5
143 Rear seats control unit 25
144 Rear seats control unit 25
145 Trailer recognition control unit (up 2008)
Trailer hitch socket (13-pin) (from 2009)
20
146 Trailer recognition control unit 25
147 up 2008: TLC [HDS] control unit (Remote trunk closing) 30
148 up 2008: Universal Portable CTEL Interface (UPCI [UHI]) control unit 7,5
from 2009: Panoramic sliding sunroof circuit 30 connector sleeve 25
149 up 2008: Voice control system (VCS [SBS]) control unit 5
from 2009: Panoramic sliding sunroof control module 25
150 TV combination tuner (analog/digital)
Japanese version: TV/tuner connector (from 2009)
7,5
151 W221; up 2008: Electric parking brake controller unit 25
W221; from 2009: Trailer recognition control unit 20
152 W221: Rear window antenna amplifier module 7,5
115 V socket: DC/AC converter control unit 25
Relay
M Terminal 15 relay
N Terminal 15R relay
O Power outlet relay
P Heated rear window relay
Q Valid for engine 156, 157, 275, 278, 629: Circulation pump relay
S 400 Hybrid: Valid for model 221.095/195: Power electronics circulation pump relay 2
R Cigar lighter relay
S Fuel pump relay
Valid for engine 642.8 and engine 651 as of 1.6.11: Connected through the fuel pump: Refrigerant compressor magnetic clutch
S 400 Hybrid: Power electronics circulation pump relay 1

Interior prefuse box (up 2008)

Mercedes-Benz S-Class - w221 - fuse box diagram - interior prefuse box
Mercedes-Benz S-Class – w221 – fuse box diagram – interior prefuse box
Number Fused Function Ampere ratting [A]
1 Starter 400
2 Not valid for engine 642:
Alternator
150
Valid for engine 642:
Alternator
200
3 150
4 AAC with integrated control additional fan motor 150
5 Valid for engine 642: PTC heater booster 200
6 Front SAM control unit with fuse and relay module 200
7 ESP control unit 40
8 ESP control unit 25
9 Front SAM control unit with fuse and relay module 20
10 Vehicle power supply control unit 7,5

Interior prefuse box (from 2009)

Mercedes-Benz S-Class - w221 - fuse box diagram - interior prefuse box
Mercedes-Benz S-Class – w221 – fuse box diagram – interior prefuse box
Number Fused Function Ampere ratting [A]
3 Rear SAM control unit with fuse and relay module 150
4 ECO start/stop function:
ECO start/stop function relay
S 400 Hybrid:
DC/DC converter control unit
Heated windshield:
Heated windshield control unit
150
5 Valid for model 221 (Electrical preinstallation for rental vehicle):Special vehicle multifunction control unit (SVMCU [MSS]) 40
S 400 Hybrid: Vacuum pump 80
6 Right dashboard fuse box 80
7 Valid for model 221 with engine 629, 642, 651:
PTC heater booster
Valid for model 221 (Electrical preinstallation for rental vehicle):
Special vehicle multifunction control unit (SVMCU [MSS])
150
8 Front SAM control unit with fuse and relay module 80
9 Left dashboard fuse box 80
10 Rear SAM control unit with fuse and relay module 150

Engine compartment prefuse box (up 2008)

Mercedes-Benz S-Class - w221 - fuse box diagram - engine compartment prefuse box
Mercedes-Benz S-Class – w221 – fuse box diagram – engine compartment prefuse box
Number Fused Function Ampere ratting [A]
1 Front prefuse box
(via on-board electrical network line pyrofuse
2 Heated windshield control unit 125
3 Right instrument panel fuse box 80
4 Rear SAM control unit with fuse and relay module 200
5 Special vehicle multifunction control unit (SVMCU [MSS]) 100
6 Rear SAM control unit with fuse and relay module 150
7 Front SAM control unit with fuse and relay modul 100
8 Left instrument panel fuse box 80
9 Front SAM control unit with fuse and relay module 5
10 C216: Emergency call system control unit 5

Engine compartment prefuse box (from 2009)

Mercedes-Benz S-Class - w221 - fuse box diagram - engine compartment prefuse box
Mercedes-Benz S-Class – w221 – fuse box diagram – engine compartment prefuse box
Number Fused Function Ampere ratting [A]
2 Alternator 460
3 Electrohydraulic power steering
Valid for model 221 with engine 629, 642:
Glow time output stage
150
4 Interior prefuse box ( unfused)
5 AAC with integrated control additional fan motor 100
6 Front SAM control unit with fuse and relay module 150
7 ESP control unit 
S 400 Hybrid: Regenerative braking system control unit
40
8 ESP control unit
S 400 Hybrid: Regenerative braking system control unit
25
9 Front SAM control unit with fuse and relay module 25
10 Spare

AdBlue fuse block

Mercedes-Benz S-Class - w221 - fuse box diagram -  adblue fuse block
Mercedes-Benz S-Class – w221 – fuse box diagram – adblue fuse block
Number Fused Function Ampere ratting [A]
A AdBlue® control unit 7,5
B Heater circuit 1 20
C Heater circuit 1 20
D Spare

WARNING: Terminal and harness assignments for individual connectors will vary depending on vehicle equipment level, model, and market.