GMC Sierra (2021 – 2022) – fuse box diagram
Year of production: 2019, 2020
Engine Compartment Fuse Block
The engine compartment fuse block is in the engine compartment, on the driver side of the vehicle.

| № | Usage |
|---|---|
| 1 | High-beam left |
| 2 | High-beam right |
| 3 | Headlamp left |
| 4 | Headlamp right |
| 6 | – |
| 7 | – |
| 8 | Fog Lamp |
| 9 | – |
| 10 | – |
| 11 | Police Upfitter |
| 12 | – |
| 13 | Washer Front |
| 14 | Washer Rear |
| 15 | – |
| 16 | – |
| 17 | IECL 1 |
| 19 | DC/AC Inverter |
| 20 | IECR 2 (LD)/EBCM 2 (HD) – Electronic Brake Control Module |
| 21 | – |
| 22 | IECL 2 |
| 24 | Electronic Brake Control Module 1 |
| 25 | – |
| 26 | – |
| 27 | Horn |
| 28 | – |
| 29 | – |
| 30 | – |
| 31 | – |
| 32 | Rear Window Defogger |
| 33 | Heated Mirror |
| 34 | Parking Lamp Left |
| 37 | – |
| 38 | – |
| 39 | – |
| 40 | Misc ignition |
| 41 | Trailer Parking Lamp |
| 42 | Park Lamp Right |
| 44 | – |
| 45 | – |
| 46 | Engine Control Module Ignition |
| 47 | Transmission Control Module Ignition |
| 48 | – |
| 49 | Transmission Control Module |
| 50 | A/C Clutch |
| 51 | Transfer Case Control Module |
| 52 | Front Wiper |
| 53 | Center High-mounted Stop Lamp |
| 54 | Trailer Reverse Lamp |
| 55 | Trailer Back-up Lamp |
| 56 | Semi Active Damping System |
| 57 | Side Blind Zone Alert |
| 58 | Starter motor (LD and HD DSL) |
| 60 | Active Fuel Management 1 |
| 61 | Vehicle Emission System |
| 62 | Integrated Chassis Control Module/CVS – Canister Vent Solenoid |
| 63 | Trailer Battery |
| 65 | Auxiliary Underhood Electrical Center |
| 66 | Cooling Fan Motor Left |
| 67 | Active Fuel Management 2 |
| 68 | – |
| 69 | Starter Pinion (LD)/ Starter Motor (HD Gas) |
| 71 | Cooling Fan |
| 72 | Cooling Fan Right/Lower |
| 73 | Trailer Stop/Turn Lamp Left |
| 74 | Trailer Interface Module 1 |
| 75 | Diesel Exhaust Fluid Controller |
| 76 | Electric RNG BDS |
| 78 | Engine Control Module |
| 79 | Auxiliary Battery |
| 80 | Cabin Cooling Pump |
| 81 | Trailer Stop/Turn Lamp Right |
| 82 | Trailer Interface Module 2 |
| 83 | Fuel Tank Zone Module |
| 84 | Trailer Brake |
| 85 | Engine |
| 86 | Engine Control Module |
| 87 | Injector B Even |
| 88 | O2 B Sensor |
| 89 | O2 A sensor |
| 90 | Injector A Odd |
| 91 | Engine Control Module Throttle Control |
| 92 | Aeroshutter |
| Relays | |
| 5 | Headlamp |
| 18 | DC/AC inverter |
| 23 | Rear window defogger |
| 35 | Parking lamp |
| 36 | Run/Crank |
| 43 | – |
| 59 | A/C clutch |
| 64 | Starter Motor (LD & HD DSL) |
| 70 | Starter Pinion (LD) / Starter Motor (HD Gas) |
| 77 | Powertrain |
| 77 | Powertrain |
Instrument Panel Fuse Block (Left)

| № | Usage |
|---|---|
| F1 | Rear Heated Seats Left/ Right |
| F3 | – |
| F4 | – |
| F5 | Multifunction End Gate |
| F6 | Heated and Ventilated Seats Left/Right |
| F8 | – |
| F9 | Passive Entry Passive Start/ Spare |
| F10 | – |
| F11 | – |
| F12 | Passenger Power Seat |
| F13 | Export Power Take Off/ Special Equipment Option 1 |
| F14 | – |
| F15 | – |
| F16 | Amplifier |
| F17 | – |
| F18 | – |
| F20 | Endgate |
| F22 | Rear Sliding Window |
| F23 | – |
| F24 | – |
| F25 | – |
| F26 | – |
| F27 | – |
| CB1 | – |
| Relays | |
| K1 | Rear Sliding Window Open |
| K2 | Rear sliding Window Close |
| K3 | Multifunction End Gate Major 1 |
| K4 | Multifunction End Gate Major 1 |
| K5 | Multifunction End Gate Minor 2 |
| K6 | Multifunction End Gate Minor 2 |
| K7 | – |
| K8 | – |
| K6 | MFEG major 2 |
| K7 | Anti-theft |
| K8 | Not Used |
Instrument Panel Fuse Block (Right)

| № | Usage |
|---|---|
| F1 | Right Doors |
| F2 | Left Doors |
| F3 | Universal Garage Door Opener |
| F4 | – |
| F5 | – |
| F6 | Front Blower |
| F8 | Lumbar Switch |
| F10 | Body Control Module 6/ Body Control Module 7 |
| F11 | Seat/Column Lock Module |
| F12 | Body Control Module 3/ Body Control Module 5 |
| F14 | Mirrors/Windows Module |
| F17 | Steering Wheel Controls |
| F18 | Video Processing Module/ Obstacle Detection |
| F19 | Discrete Logic Ignition Switch (DLIS) |
| F20 | Ventilated Seats |
| F21 | NOT R/C |
| F22 | Heated Steering Wheel |
| F23 | MISC R/C |
| F24 | 2021: Instrument panel cluster ignition/Overhead 2022: Power Take Off/Reflective Light Auxiliary Display/ Instrument Panel Cluster/ Central Gateway Module/ Inside Rear View Mirror/ Overhead Console Module Ignition |
| F25 | Heating, Ventilation, and Air Conditioning Ignition/ Heating, Ventilation, and Air Conditioning Auxiliary |
| F26 | USB Ports/Special Equipment Option Retained Accessory Power |
| F27 | Accessory Power Outlet/ Retained Accessory Power |
| F28 | Accessory Power Outlet/ Battery |
| F30 | Sensing and Diagnostic Module/Parking Brake |
| F31 | Body Control Module 4 |
| F32 | Special Equipment Option/ Data Link Connection |
| F33 | Body Control Module 8 |
| F34 | Cargo Lamp |
| F40 | Central Gateway Module (CGM) |
| F41 | Infotainment 1 |
| F42 | Telematics Connectivity Platform |
| F43 | – |
| F44 | 2021: Active vibration management |
| F45 | Body Control Module 2 |
| F46 | Heating, Ventilation, and Air Conditioning/Battery 1 |
| F47 | Instrument Panel Cluster/ Battery |
| F48 | Transmission Control Module |
| F49 | Body Control Module 1 |
| F50 | – |
| F51 | Battery 1 |
| F52 | Battery 2 |
| F53 | – |
| F54 | Sunroof |
| F55 | Driver Power Seat |
| F56 | DC DC TRANS 1 |
| F57 | DC DC TRANS 2 |
| F58 | Infotainment 2 |
| CB1 | Accessory Power Outlet 2 |
| CB2 | Accessory Power Outlet 1/ Cigarette Lighter |
| CB3 | 2021: Accessory power outlet 3 |
| CB4 | 2021: Accessory power outlet 4 |
| Relays | |
| K1 | Run/Crank |
| K2 | Retained Accessory Power/ Accessory 1 |
| K4 | 2021: Retained accessory power/ Accessory 2 |
| K5 | – |
| K1 | Run/Crank |
| K2 | Retained accessory power/Accessory 1 |
| K4 | Retained accessory power/Accessory 2 |
| K5 | Not Used |
WARNING: Terminal and harness assignments for individual connectors will vary depending on vehicle equipment level, model, and market.
